Globes is reporting that Virgin Atlantic will begin service between London/LHR and Tel Aviv on 9/25/19. This has been rumored ever since it was announced last June that Shai Weiss, an Israeli, would become CEO of Virgin Atlantic. He began the new job last month.
Heathrow to Tel Aviv already sees 4 daily widebodies between British Airways and El Al and there is lots of competition from other London area airports, but Virgin clearly sees the opportunity here.
Connections will be available from many US cities to Tel Aviv via their London hub and lie-flat seats will be available in business class on both legs.
London-Tel Aviv will be the shortest flight in the Virign Atlantic network.
You can transfer miles from AMEX, Chase, Citibank, or Marriott to Virgin Atlantic, though they do collect fuel surcharges on award tickets for their own flights. However there are often transfer bonuses from AMEX and Citibank to Virgin Atlantic and they Virgin Atlantic also has award sales that may make this a worthwhile redemption, so stay tuned for those.